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Endothelin: Molecular Biology, Physiology, and Pathology by David M. Pollock (auth.), Robert F. Highsmith (eds.)

By David M. Pollock (auth.), Robert F. Highsmith (eds.)

In Endothelin: Molecular Biology, body structure, and Pathology, educational, scientific, and business researchers summarize the dramatic fresh growth that has been documented in endothelin examine and point out the optimum course of destiny reports. The members, hugely revered experts of their fields in addition to energetic bench scientists, produce a serious assessment and synthesis of our wisdom of endothelin chemistry and pharmacology, its mechanism of motion, and its physiological capabilities.

Endothelin: Molecular Biology, body structure, and Pathology is sure to develop into the hot ordinary reference resource for either uncomplicated scientists and trained clinicians who desire a transparent suggestion of the jobs endothelin may well play in cardiovascular body structure and pathology. Biochemists, in addition to medicinal and medical chemists, inquisitive about the advance of gear designed to change the motion or expression of the endothelin molecule will locate the publication wealthy in new effects and insights.


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Extra info for Endothelin: Molecular Biology, Physiology, and Pathology

Sample text

J. Pharmacol. 163:379--382. 83. , Johnson, C. , Chai, S. , Casley, D. , and Mendelsohn, F. A. 0. (1989) Localization of endothelin receptors in rat kidney. Eur. J. Pharmacol. 160:193,194. 84. , and D'Orleans-Juste, P. (1993) Endothelin-1 induces vasoconstriction and prostacyclin re1ease via the activation of endothelin ETA receptors in the perfused rabbit kidney. Eur. J. Pharmacol. 237:275-281. 85. , and Yamamoto, K. (1991) Effects of endothelin-3 on renal functions. J. Pharmacol. Exp. Ther. 259:1256-1260.

Peptides 16:139--144. 132. , Thai, Q. , Kassell, N. , and Lee, K. S. (1994) Cerebra! microvascular responses to endothelins: the role of ETA receptors. Brain Res. 658: 179-184. 133. , and Robertson, R. M. ( 1992) Endothelirr as a neuropeptide. Cardiovascular effects in the brainstem ofnormotensive rats. Cire. Res. 72:20-35. 134. , and Yazaki, Y. (1989) Central effect of endothelirr on blood pressure in conscious rats. Am. J. Physiol. 256: H1747-H1751. 135. Takuwa, Y. (1993) Endothelirr in vascular and endocrirre systems: biological activities and its mechanisms of action.

T. (1992) Endothelin and structurally related analogs distinguish between endothelin receptor subtypes. Biochem. Biophys. Res. Comm. 183:1566--1571. 117. Buchan, K. , Rabe, K. , Sumner, M. , and Watts, I. S. (1994) Characterisation of the endothelin receptor mediating contraction ofhuman pulmonary artery using BQ123 and Ro 46-2005. Eur. J. Pharmacol. 260:221-225. 118. Knott, P. , D' Aprile, A. , Henry, P. , Hay, D. W. , and Goldie, R. G. (1995) Receptors for endothelin-1 in asthmatic human periphera11ung.

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