By Robert A. Soslow M.D. (auth.), Robert A. Soslow, Carmen Tornos (eds.)
Diagnostic Pathology of Ovarian Tumors deals a spotlight at the pathology of ovarian neoplasia with particular clinically proper info for training pathologists now not present in different extra normal volumes of gynecologic pathology. this crucial paintings focuses nearly completely on innovations for actual analysis and histologic subclassification, and the medical correlates of those diagnoses. It presents evolving directions for detecting early ovarian melanoma in prophylactic specimens; state-of-the-art info on bettering the reproducible and clinically significant subclassification of ovarian carcinoma in addition to new proposals for ovarian carcinoma grading. Richly illustrated, containing ample tables and figures in addition to bulleted issues of data, Diagnostic Pathology of Ovarian Tumors is the 1st textual content supplying chapters written by way of training gynecologists on how medical information can improve pathologic diagnostic accuracy, how pathologists can successfully express their diagnostic evaluations to gynecologists, and how during which a given analysis triggers a cascade of medical checking out and remedy.
Diagnostic Pathology of Ovarian Tumors might be of significant worth to training surgical pathologists, together with gynecologic pathologists, pathology citizens in education, in addition to gynecologic and scientific oncologists around the globe.
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Extra info for Diagnostic Pathology of Ovarian Tumors
The cystic pattern with flat epithelium is composed of cysts of variable sizes, with little intervening stroma, and some intraluminal secretion, and are lined by predominantly flat cells, deceivingly benign in appearance. The diagnosis can be suspected in the presence of isolated plumper atypical nuclei, which may be scanty (Fig. 36a–c). Additional sections from other parts of the tumor may be diagnostically helpful if they contain patterns that are characteristic of clear cell carcinoma, like solid nests of clear cells or papillae with hob-nail cells and hyalinized fibrovascular cores.
25. 26). Since the cytologic appearance of these three tumors is different, an appreciation of these features can help in the differential diagnosis. A scraping at the time of FS can be very helpful. 26). 27). 28a–c). Endometrioid variant of yolk sac tumor is rare and is seen in young patients, age 11–34 (mean, 22 years). The age is a helpful diagnostic feature. Features that favor the diagnosis of yolk sac 28 C. A. 27  (Fig. 29a, b). Increased serum level of alpha-fetoprotein is also helpful.
Mod Pathol. 1999;12:933–40. 25. Zhao C, Bratthauer GL, Barner R, et al. Comparative analysis of alternative and traditional immunohistochemical markers for the distinction of ovarian Sertoli cell tumors, from endometrioid tumors, and carcinoid tumor. Am J Surg Pathol. 2007;31:255–66. 26. McCluggage WG, Young RH. Ovarian Sertoli-Leydig cell tumors with pseudo-endometrioid tubules. Am J Surg Pathol. 2007;31:592–7. C. A. Soslow 27. Misir A, Sur M. Sertoliform endometrioid carcinoma of the ovary: a potential diagnostic pitfall.