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Current Research in Ophthalmic Electron Microscopy by I. Grierson, W. R. Lee (auth.), Professor Dr. Manfred

By I. Grierson, W. R. Lee (auth.), Professor Dr. Manfred Spitznas (eds.)

The learn of ocular nice constitution lower than physiologic and experimental stipulations is a comparatively younger department of ophthalmic examine, requiring a excessive measure of specialization. The few scientists, who're taken with this type of learn are generally scattered via­ out Europe. as a result, the alternate of medical info, that's important for crit­ ical review and carrying on with stimulation of person paintings, is usually impeded. In an at­ tempt to beat this challenge, a gaggle of likeminded study employees acquired jointly in Essen in spring 1972 and based ECOFS, the eu membership for Ophthalmic fantastic Struc­ ture. due to the fact its inauguration the membership has attracted the curiosity of progressively more scientists engaged within the electron microscopic research of the attention. as soon as every year the contributors of the organization and invited site visitors participate in a really energetic clinical assembly. in the course of those workshops the individuals have considerable oppurtunity to file intimately at the contemporary effects bought of their investigations and to check the validity in their conclusions in full of life discussions with different experts. This booklet encompasses a nice variety of the papers provided on the 5th annual assembly of ECOFS in Zurich, Switzerland, on March 25 and 26, 1977. This stock of present examine in ophthalmic electron microscopy might serve to notify either scien­ tifically oriented ophthalmologists and different investigators operating in comparable fields of research.

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In some cases the lymphoid cells are grouped in clusters which probably correspond to the dustlike precipitates seen with the slit lamp. In addition to lymphocytes, these clusters contain numerous plasma cells and macrophages. It is not known whether these latter cells are cells of the donor or of the recipient. Fig. 5. Lymphocytes lying under the endothelial cells, leaving only holes on the surface (3rd day, x 3000) Lymphocytes on Corneal Endothelium 51 By the sixth day there are no more lymphocytes.

Jap. J. Ophthal. A: Ultrastructural studies of the blood-aqueous barrier. II. The barrier to horseradish peroxidase in primates. Amer. J. Ophthal. A: Further observations on the fine structure of freeze-cleaved tight junctions. J. Cell Sci. : An epithelial blood-aqueous barrier to horseradish peroxidase in the ciliary processes of the vervet monkey (Cercopithecus aethiops). Z. Zellforsch. -P. Harnisch University Eye Hospital, (Head: Prof. Dr. Hager, Klinikum Steglitz, Freie Universitat Berlin, Hindenburgdamm 30, 0-1000 Berlin 45 Summary.

With TEM (Fig. 6), these lymphocytes have a handmirror shape, with the handle to the rear. The nucleus is in the anterior part of the cell and there is usually a small pseudopod in front of it. Most often the lymphocytes reach Descemet's membrane without altering it. This raises the problem of the antigenicity of this membrane. By the third day the endothelium has largely been destroyed and progressively detached from Descemet's membrane, and lymphocytes migrate under the endothelial cells. Some activated lymphocytes are visible attacking their target (Fig.

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