By Jonathan Gillard, Dr Martin Graves, Thomas Hatsukami, Chun Yuan
Stroke is a big reason behind morbidity and mortality, with carotid ailment representing an incredible contributory hazard issue. This booklet bargains complete assurance of the pathogenesis and administration of carotid sickness with particular specialise in the function imaging has to play within the early popularity of symptomatic and asymptomatic ailment in addition to the therapy of the built . Technological advances in imaging modalities now let unique research of the sickness development, the prediction of severe occasions resulting in a stroke, in addition to the identity of the simplest surgical or different interventional remedies. This e-book could be learn by way of neurologists, cardiologists, vascular surgeons, neurosurgeons and radiologists occupied with the care of sufferers with carotid illness, and in addition by way of researchers focused on the advance of recent healing options and drugs.Stroke is an important reason for morbidity and mortality, with carotid illness representing a big contributory hazard issue. This e-book deals complete insurance of the pathogenesis and administration of carotid sickness with particular specialise in the function imaging has to play within the early reputation of symptomatic and asymptomatic sickness in addition to the remedy of the constructed situation. It discusses the technological advances in imaging modalities which now permit distinctive research of the disorder development, the prediction of serious occasions resulting in a stroke, in addition to the id of the simplest surgical or different interventional remedies. hugely illustrated all through with major specialist individuals, this publication could be learn by means of neurologists, cardiologists, vascular surgeons, neurosurgeons and radiologists concerned with the care of sufferers with carotid disorder, and in addition through researchers excited about the improvement of latest healing thoughts and medication.
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Extra info for Carotid Disease: The Role of Imaging in Diagnosis and Management
Is luminal narrowing the only determinant of vulnerability of a plaque? Vulnerable plaque is a concept well accepted in the coronary circulation but not so well established in the carotid plaque. In studies carried out in the coronary circulation it has been shown that plaque ruptures often occur at low degrees of luminal narrowing and that percent stenosis is a poor predictor of plaque rupture. Ambrose et al. , 1988). , 1995). Wasserman et al. 8). , 2005). , 2001). 9). 6 Calcification and bone formation in atherosclerotic plaques.
The pathological characteristics of carotid artery atherosclerosis are described in elegant detail by Virmani et al. in Chapter 1. Here, we review the epidemiology of carotid artery atherosclerosis, including its distribution, determinants and risks conferred by its presence. The available evidence demonstrates that carotid artery atherosclerosis is common and high risk, and the identification and treatment of carotid artery atherosclerosis may substantially reduce the burden of cardiovascular disease.
Burke, A. , Tracy, R. , et al. (2002). Elevated C-reactive protein values and atherosclerosis in sudden coronary death: association with different pathologies. Circulation, 105, 2019À23. , Pearce, W. , Virmani, R. and Yao, J. S. (1996). Atherosclerotic plaque rupture in symptomatic carotid artery stenosis. Journal of Vascular Surgery, 23, 755À65; discussion 765À756. , Ferguson, M. , et al. (2004). Hemorrhage in the atherosclerotic carotid plaque: a F. B. (2003). Durability of carotid endarterectomy.