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Bronchopulmonary Dysplasia, Volume 240 (Lung Biology in by Steven H. Abman

By Steven H. Abman

Rising cures for BPD - comparable to Inhaled Nitrous Oxide, nutrition A, Antioxidant recommendations, and low-dose steroid treatment

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Additional info for Bronchopulmonary Dysplasia, Volume 240 (Lung Biology in Health and Disease)

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Maybe EGFR is part of a mechanic stimulus signal sensor during fetal lung development (147). Aberrant expression of matrix metaloprotease proteins (MMPs) is also detected in EgfrÀ/À null mutant mice, which suggests that MMPs may be involved in EGFR-regulated lung growth (148). TNF-a-converting enzyme (TACE) is a transmembrane metalloproteasedisintegrin that functions as a membrane sheddase to release the ectodomain portions of many transmembrane proteins, including the precursors of TNFa and several other cytokines, as well as the receptors for TNFa, and neuregulin (ErbB4) (149).

Kim CF, Jackson EL, Woolfenden AE, et al. Identification of bronchoalveolar stem cells in normal lung and lung cancer. Cell 2005; 121:823–835. 36. DeLanghe S, Carraro G, Warburton D, et al. Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol 2006; 299:52–62. 37. Shan L, Subramanian M, Emanuel RL, et al. Centrifugal migration of mesenchymal cells in embryonic lung. Dev Dyn 2008; 237:750–757. 38. Qian X, Costa RH. Analysis of hepatocyte nuclear factor-3 beta protein domains required for transcriptional activation and nuclear targeting.

Developmental shift in the relative percentages of lung fibroblast subsets: role of apoptosis postseptation. Am J Physiol 1999; 277:L848–L859. 24. Schittny JC, Djonov V, Fine A, et al. Programmed cell death contributes to postnatal lung development. Am J Respir Cell Mol Biol 1998; 18:786–793. 25. Srinivasan S, Strange J, Awonusonu F, et al. Insulin-like growth factor I receptor is downregulated after alveolarization in an apoptotic fibroblast subset. Am J Physiol Lung Cell Mol Physiol 2002; 282:L457–L467.

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