By Stephen M. Bonsib (auth.)
The kidney is an organ with advanced organogenesis at risk of various misadventures in improvement and is uncovered to a various array of insults of hematogenous and reduce urinary tract beginning. This Atlas of scientific Renal Pathology presents an summary of the improvement, macroscopic and microscopic good points of the traditional kidney. this can be by means of a finished survey of developmental and cystic kidney ailments, vascular ailments and tubulointerstitial illnesses. An emphasis is put on gross diagnostic findings with unique histological correlates. furthermore, the histological, immunofluorescent, immunohistochemical and ultrastructural gains of the key glomerular ailments and renal transplantation pathology are awarded. This compendium of non-neoplastic kidney ailments illustrates the overwhelming majority ailments you will definitely stumble upon in surgical and post-mortem pathology.
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Additional resources for Atlas of Medical Renal Pathology
The interstitium shows fibrosis and calcification Fig. 56 ADPKD. This case of advanced ADPKD shows multiple large cysts. 3 Acquired Cystic Kidney Disease ACKD is defined by the presence of three or more cysts, bilaterally, in the native kidneys of patients with ESKD whose original disease was not the result of a cystic kidney disease. Development of ACKD is common among dialysis patients, and its incidence increases over time. By 10 years on dialysis, most patients will be affected. A major concern with ACKD is development of renal cell carcinoma (RCC), which will occur in approximately 10 % of affected patients.
In children with ARPKD, the cortical collecting cysts may be small and usually are rounded in profile. There also is ectasia of other tubules, likely proximal tubules. Most cysts are located in the renal medulla, affecting concentration function 34 Fig. 43 ARPKD, neonatal onset. The liver in neonatal ARPKD has a characteristic bile duct plate abnormality. The bile ducts reside in an expanded portal triad and are peripherally arrayed and branched. This liver abnormality may be a useful finding in cases in which the renal lesion is less severe and the diagnosis is more challenging.
1 Abnormalities in Form, Position, and Number 21 Fig. 4 Horseshoe kidney. This horseshoe kidney is from a child. It shows limited fusion of the lower poles. The renal pelves are markedly abnormal. Both pelves are extrarenal. The right pelvis is bifid, and the left pelvis is trifid with a narrow connecting portion Fig. 6 Dysplastic horseshoe kidney. This is an example of renal fusion associated with bilateral renal dysplasia. There was urethral atresia resulting in megacystis and massively dilated proximal hydroureters.