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Atlas of Liver Pathology by Anthony W. H. Chan, Alberto Quaglia, Beate Haugk, Alastair

By Anthony W. H. Chan, Alberto Quaglia, Beate Haugk, Alastair Burt

The liver is a posh organ because of its targeted microscopic constitution, problematic metabolic services and susceptibility to a wide selection of insults, manifesting in numerous histological  patterns.  Atlas of Liver Pathology considers either alterations obvious in scientific liver biopsies in addition to lesional biopsies while the specimen has been taken from a mass. The publication starts off by way of reviewing common constitution and its versions and the optimum ways for the training of histological sections for diagnostic liver pathology. the subsequent chapters are devoted to developmental, metabolic, infectious, drug comparable, autoimmune, biliary, vascular and neoplastic issues. sections on liver pathology in being pregnant and transplantation finish the paintings. Macroscopic illustrations are incorporated the place acceptable. All pictures are complemented by way of legends describing the image and supplying suitable similar information.

Authored through nationally and the world over well-known pathologists, Atlas of Liver Pathology is a priceless source that serves as a brief reference advisor for the analysis of ordinary and weird diseases.

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Caroli disease may be associated with extrahepatic biliary dilatation and is considered one form (type V) of choledochal cyst. Clinical presentations are associated with the principal complications, namely acute cholangitis and hepatolithiasis. Portal hypertension occurs in Caroli syndrome and usually precedes episodes of acute cholangitis. Caroli disease is associated with an overall risk of 7% to 15% for developing cholangiocarcinoma. 2 Fibrocystic Liver Disease and Choledochal Cyst Fig. 20 Caroli disease.

Clinical presentations are associated with the principal complications, namely acute cholangitis and hepatolithiasis. Portal hypertension occurs in Caroli syndrome and usually precedes episodes of acute cholangitis. Caroli disease is associated with an overall risk of 7% to 15% for developing cholangiocarcinoma. 2 Fibrocystic Liver Disease and Choledochal Cyst Fig. 20 Caroli disease. A cystically dilated bile duct is eroded and filled with inspissated bile sludge. Caroli disease is characterised by multiple segmental dilatations of the intrahepatic biliary tree.

The cystic type of IPNB is characterised by cystic ductal dilatation by mucinous epithelial cells with variable cytologic and architectural atypia, with prominent intraductal mucin accumulation, direct luminal connection to the bile ducts, and absence of the ovarian-type stroma. Fig. 19 Caroli disease. Cystically dilated bile ducts with irregular contours are present. One of these (right) contains an intraluminal protrusion of ductal wall with a fibrovascular core. Caroli disease mostly commonly is associated with autosomal recessive polycystic kidney and, rarely, ADPKD.

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