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Atlas of Bone Marrow Pathology by B. Frisch, R. Bartl (auth.)

By B. Frisch, R. Bartl (auth.)

Examination of the bone marrow has continually been, and to-date concepts whose software will certainly to a wide volume nonetheless is, in the area of the haema­ raise sooner or later. tologist. the reason for this is that smears of bone marrow aspirates After long discussions and enquiries, the belief including peripheral blood motion pictures and result of different was once reached that the magnifications of lots of the exams and investigations supplied the knowledge on which illustrations might be passed over with no detracting from the usefulness of the Atlas. The magnifications used are the medical analysis was once established. lately, the common availability of either enhanced indicated in Fig. 1.25. additionally, now not each aspect specif­ biopsy needles and strategies for processing has enormously ically indicated in a determine or its legend is unavoidably elevated the variety of often taken bone biopsies pointed out within the textual content; and infrequently quite a number observations and positioned the exam of bone marrow biopsy is illustrated and in those situations the legends are self­ sectiors additionally within the box of histopathology - in order that explanatory. this Atlas is without doubt one of the present Histopathology sequence. This Atlas is directed to haematologists and to histo­ consequently, the haematologist and the histopathologist pathologists and to a person attracted to the research now supplement one another within the interpretation of bone and realizing of the human bone marrow. marrow smears, imprints and sections, therefore using all to be had info and services to reach at a diagnosis.

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Philadelphia Lea and Febiger 36. Mangan, K. F (1985). T-cell-mediated suppression of haematopo iesis. N Eng!. J Med, 312, 306 37. Nienhuis, A W (1988). Haematopoietlc growth factors. Biologic complexity and clinical promise. N. Engl. J Med, 318, 916 32 BIOLOGY. STRUCTURE AND COMPONENTS OF NORMAL BONE MARROW 38. Navone. R.. Azzoni. L. and Valente. G. (1988). Immunohistochemical assessment of ferritin in bone marrow trephine biopsies: correlation with marrow haemosiderin. Acta Haematol.. 80. 194 39.

There is a very heterogeneous group of possible aetiologies for aplastic anaemia, but in most cases the cause is not reflected in the bone marrow picture, and in many patients the aetiology remains obscure in spite of extensive investigations. The aplastic anaemia associated with pancytopenia presumably arises from a defective stem cell (or pluripotent precursor cell) as distinct from isolated reductions in red cells, in granulocytes or in platelets which result from failure of proliferation and differentiation of the committed precursors which produce these cell lines.

And Davis. H. P. (1985). Thrombocytopenia in hypothermia: a common but poorly recognised complication. Br Med J, 291, 23 36. , Lewis. , Burkhardt. R. and Bartl. R. (1985). BiopsV Pathology of Bone and Bone Marrow. (London: Chapman and Hall) 37. , Sumiyoshi, A.. Hayashi. , Suzumlya, J. and Kaketani, K. (1985). Immunohistochemistry of vascular lesion in thrombotic thrombocytopenic purpura, with special reference to Factor VIII related antigen. Thromb. , 3S, 469 38. De la Serna. F. J, Gilsanze, F..

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