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Advances in Pharmacological Research and Practice. by J. Knoll and K. Kelemen (Eds.)

By J. Knoll and K. Kelemen (Eds.)

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Extra resources for Advances in Pharmacological Research and Practice. Proceedings of the 4th Congress of the Hungarian Pharmacological Society, Budapest, 1985

Example text

Soc. Budapest 1985 Vol. 1. Sect. 1. Pharmacological Protection of the Myocardium L Szekeres, J. Gy. Papp (eds) REFLECTIONS ON THE MODE OF ACTION OF BETA-ADRENOCEPTOR ANTAGONISTS IN PROLONGING LIFE AFTER ACUTE MYOCARDIAL INFARCTION J. D. FITZGERALD 10! , UK The role of beta adrenoceptor blocking drugs /ßB/ in the treatment of acute myocardial infarction /AMI/ has been the subject of controversy for more than 20 years. Many experimen­ tal observations have shown that both regional myocardial ischaemia and catecholamines can precipitate lifethreatening cardiac arrhythmias /Schwartz 1985/.

Takeda,K. , 1984, Anti-arrhythmic effects of (-)-camitine chloride and its acetyl analogue on canine late ventricular arrhythmia induced by ligation of the coronary artery as related to improvement of mitochondrial function. Pharmacol. 82:533-542. , Ishii,M. , 1985, Antiarrhythmic effects of coronary vasodilators on canine ventricular arrhythmia models. Pharmacol. 38:73-82. , Kanaide,H,, Yoshimura,M. , 1981, A protective effect of coenzyme on ischemia and reperfusion of the isolated perfused rat heart.

J,: Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias. Nature 291, 323-324, /1981/ Danon A. : Inhibition of prostaglandin bio­ synthesis by corticosteroids requires RNA and protein synthe­ sis. Nature 273, 552-554, /1978/ Di Rosa M. J. Pharmac. , Oelz O.. S. J,: Anti-inflainmatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation. , Párente L.. Di Rosa M. Commun. , Solomon D. : A phospholipase A9 inhibitory protein in rabbit neutrophils induced by glucocorticoids, Proc.

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